Texas Tech defeated Kansas State 43-20 in Week 10, with the Red Raiders' defense providing crucial stops throughout the contest. Texas Tech quarterback Behren Morton led the passing attack with 249 yards, while receiver Caleb Douglas recorded 82 receiving yards. Kansas State's Avery Johnson rushed for 88 yards in the losing effort.

The game remained competitive early, with Kansas State scoring first on a 46-yard rushing touchdown by Johnson in the first quarter. Texas Tech, however, controlled the second half, particularly the third quarter where the Red Raiders' defense generated multiple high-impact plays. Texas Tech's defense forced several critical stops, including a fourth-quarter fumble recovery by Kansas State's R. Davis that resulted in a significant momentum swing.

Texas Tech's offense responded with multiple scoring drives, including a 41-yard rushing touchdown by J. Williams. The Red Raiders' balanced attack and defensive pressure proved decisive. Texas Tech covered the 7-point spread, and the game went over the 52-point over-under line at 63 total points.